159752-17-7Relevant academic research and scientific papers
Synthesis of enantiomerically pure 4-acetoxy-2-fluoro-2-cyclopenten-1-one
Sato,Hirokawa,Hattori,Toyota,Kaneko
, p. 975 - 980 (2007/10/02)
Addition of molecular fluorine to cis-2-cyclopentene-1,4-diol gave the cis-anti adduct stereoselectively. This meso diol was dissymmetrized by means of acetylation under lipase catalysis to afford the monoacetate with a high enantiomeric purity. Oxidation of the monoacetate followed by elimination of hydrogen fluoride under basic conditions furnished the titled compound which is an attractive building block for chiral fluorinated molecules.
