159752-17-7

Basic information

• Product Name: 2-Cyclopenten-1-one,4-(acetyloxy)-2-fluoro-,(R)-(9CI)
• Synonyms: 2-Cyclopenten-1-one,4-(acetyloxy)-2-fluoro-,(R)-(9CI)
• CAS NO: 159752-17-7
• Molecular Formula: C7H7FO3
• Molecular Weight: 158.13
• Product Categories: HALIDE
• Mol File: 159752-17-7.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-Cyclopenten-1-one,4-(acetyloxy)-2-fluoro-,(R)-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Cyclopenten-1-one,4-(acetyloxy)-2-fluoro-,(R)-(9CI)(159752-17-7)
• EPA Substance Registry System: 2-Cyclopenten-1-one,4-(acetyloxy)-2-fluoro-,(R)-(9CI)(159752-17-7)

Safety Data

• Hazardous Substances Data: 159752-17-7(Hazardous Substances Data)

Upstream product

• 159752-11-1 (1S*,2R*,3S*,4R*)-1,4-diacetoxy-2,3-difluorocyclopentane 
• 159752-15-5 (1S,2R,3S,4R)-4-acetoxy-2,3-difluorocyclopentan-1-ol 
• 159752-14-4 (1S*,2R*,3S*,4R*)-2,3-difluorocyclopentane-1,4-diol 
• 29783-26-4 cis-4-cyclopentene-1,3-diol 
• 54664-61-8 cis-1,4-diacetoxy-2-cyclopentene 
• 159752-16-6 Acetic acid (1R,2S,3R)-2,3-difluoro-4-oxo-cyclopentyl ester 

Relevant articles and documents

Synthesis of enantiomerically pure 4-acetoxy-2-fluoro-2-cyclopenten-1-one

Addition of molecular fluorine to cis-2-cyclopentene-1,4-diol gave the cis-anti adduct stereoselectively. This meso diol was dissymmetrized by means of acetylation under lipase catalysis to afford the monoacetate with a high enantiomeric purity. Oxidation of the monoacetate followed by elimination of hydrogen fluoride under basic conditions furnished the titled compound which is an attractive building block for chiral fluorinated molecules.