159766-59-3Relevant academic research and scientific papers
Borane Catalyzed Redox Isomerization of 2-Amino Chalcones: Hydride Abstraction or Hydride Migration?
Zhou, Rundong,Paradies, Jan
supporting information, p. 6334 - 6339 (2021/09/25)
The borane catalyzed redox isomerization of 2-amino chalcones was developed. The tetrahydroquinolines are obtained in high yield as a mixture of cis/trans diastereomers in a ratio of 2 : 1 to >95 : 5. The reaction mechanism is investigated by mechanistic,
Highly selective N-allylation of anilines under microwave irradiation
Liu, Meiyu,Wang, Xie,Sun, Xiaoliang,He, Wei
, p. 2711 - 2714 (2014/05/06)
An easy and rapid procedure for the preparation of a variety of mono- and bis-allylated anilines via the reaction of allyl bromide with a wide range of anilines under microwave irradiation is described. This approach allows use of mild conditions and short reaction times to give high selectivities and excellent yields.
From PtCl2- and acid-catalyzed to uncatalyzed cycloisomerization of 2-propargyl anilines: Access to functionalized indoles
Cariou, Kevin,Ronan, Baptiste,Mignani, Serge,Fensterbank, Louis,Malacria, Max
, p. 1881 - 1884 (2008/03/12)
(Chemical Equation Presented) On the move: PtCl2-catalyzed electrophilic activation of an alkyne moiety triggers a heterocyclization accompanied by migrations of both an allyl group and an acetate group to produce an indole (see scheme). Variat
Synthesis of polysubstituted indoles and indolines by means of zirconocene-stabilized benzyne complexes
Tidwell, Jeffrey H.,Buchwald, Stephen L.
, p. 11797 - 11810 (2007/10/02)
The development of a new method for the regiospecific synthesis of polysubstituted indoles and indolines is reported. The key steps involve the generation of zirconocene-stabilized benzyne complexes and subsequent intramolecular olefin insertion reactions to provide tricyclic indoline zirconacycles. The zirconacyclic intermediates were cleaved with iodine to yield diiodo indolines, which were converted to a wide variety of indole and indoline products, such as analogs of tryptamine, serotonin, tryptophan, and the pharmacophore of CC-1065.
