159799-43-6Relevant articles and documents
Cycloaddition of in situ generated 1,2-diaza-1,3-dienes with simple olefins: Facile approaches to tetrahydropyridazines
Zhong, Xingren,Lv, Jian,Luo, Sanzhong
supporting information, p. 1561 - 1564 (2015/03/30)
A catalyst-free [4 + 2] annulation process between in situ generated 1,2-diaza-1,3-butadienes and simple olefins has been developed. Under mild conditions, the reactions afforded 1,4,5,6-tetrahydropyridazines, which feature a wide range of bioactive compounds, with high yields (up to 99% yield).