1598-96-5Relevant academic research and scientific papers
A Convenient Synthesis of 2-Fluoro- and 2-Chloromalonic Esters Mediated by Hypervalent Iodine
Kitamura, Tsugio,Muta, Kensuke,Oyamada, Juzo
, p. 3241 - 3245 (2015/10/19)
Direct fluorination of malonic esters with a reagent system of iodosylbenzene and Et3N·5HF gave the corresponding 2-fluoromalonic esters in good to high yields. Direct chlorination using iodosylbenzene and hydrochloric acid also provided the 2-chloromalonates in high yields.
METHOD OF PRODUCING MONOFLUOROMALONIC ACID DERIVATIVE
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Paragraph 0038-0041, (2017/02/24)
PROBLEM TO BE SOLVED: To provide a method of producing a monofluoromalonic acid ester derivative that has a high yield, facilitates separation of a product, and allows industrial production. SOLUTION: A malonic acid ester derivative (1) is reacted with a hydrogen fluoride source in the presence of an iodosylbenzene derivative or an iodobenzene derivative and an oxidizing agent, to produce a monofluoromalonic acid derivative (4). COPYRIGHT: (C)2015,JPOandINPIT
Efficient synthesis of dissymmetric malonic acid S, O -esters via monoalcoholysis of symmetric dithiomalonates under neutral conditions
Matsuo, Kazumasa,Shindo, Mitsuru
supporting information; experimental part, p. 4406 - 4409 (2011/10/08)
A novel method for the highly selective synthesis of dissymmetric S,O-malonates starting from symmetric diphenyl dithiomalonates under neutral conditions is described. The key step is the thermal formation of an acylketene, the stability of which would co
Preparation des 2-fluoro-3,3-dihalogeno acrylates a partir des alcoxycyclopropanes polyhalogenes
Nguyen, T.,Wakselman, C.
, p. 720 - 725 (2007/10/02)
Route to 2-fluoro-3,3-dihalogenoacrylates via polyhalogenated alkoxycyclopropanes. 3,3-Dichloro- and 3,3-dibromo-2-fluoroacrylates have been prepared from alkoxy-chlorodifluoroethylene via their dihalogenocarbene adducts.The orientation of the cyclopropan
