15980-15-1

Basic information

• Product Name: 1,4-THIOXANE
• Synonyms: 1,4-Oxathiane, 98+%;1,4-Thioxane, 98% 25GR;NSC 49179;1,4-Oxathiin, 2,3,5,6-tetrahydro-;1-Oxa-4-thiacyclohexane;1-Thia-4-oxacyclohexane;Oxathiane;p-Thioxane
• CAS NO: 15980-15-1
• Molecular Formula: C₄H₈OS
• Molecular Weight: 104.17
• EINECS: 240-117-6
• Mol File: 15980-15-1.mol
• Article Data: 12

Chemical Properties

• Melting Point: -17°C
• Boiling Point: 147 °C755 mm Hg(lit.)
• Flash Point: 108 °F
• Appearance: /liquid
• Density: 1.114 g/mL at 25 °C(lit.)
• Vapor Pressure: 5.65mmHg at 25°C
• Refractive Index: n20/D 1.5095(lit.)
• Storage Temp.: Flammables area
• Water Solubility: Slightly soluble in water
• BRN: 102552
• CAS DataBase Reference: 1,4-THIOXANE(CAS DataBase Reference)
• NIST Chemistry Reference: 1,4-THIOXANE(15980-15-1)
• EPA Substance Registry System: 1,4-THIOXANE(15980-15-1)

Safety Data

• Hazard Codes: Xi
• Statements: 10-36/37/38
• Safety Statements: 16-26-27-36/37/39
• RIDADR: UN 1993 3/PG 3
• WGK Germany: 2
• RTECS: RP4200000
• TSCA: T
• HazardClass: 3
• PackingGroup: III
• Hazardous Substances Data: 15980-15-1(Hazardous Substances Data)

Usage

Description

1,4-Thioxane, also known as 1,4-oxathiane, is a clear colorless to yellow liquid with unique chemical properties. It serves as a valuable reactant and reagent in various organic reactions, particularly in the growth and characterization of certain materials.

Uses

Used in Chemical Synthesis:
1,4-Thioxane is used as a reactant and reagent for organic reactions, facilitating the synthesis of various compounds due to its unique chemical properties.
Used in Material Science:
1,4-Thioxane is used as an oxygen donor adduct to study the growth of ZnO nanowires through chemical vapour deposition. This application highlights its importance in the development of advanced materials with specific properties.
Used in Nanotechnology:
1,4-Thioxane is employed in the study and growth of vertically aligned zinc oxide (ZnO) nanowires, which are essential components in various electronic and optoelectronic devices. Its role in this process is crucial for the advancement of nanotechnology and the development of innovative applications.

Safety Profile

Moderately toxic by ingestion. Mildly toxic by inhalation. A skin and eye irritant. Flammable liquid when exposed to heat, sparks,flame, or oxidizers. Forms explosive complexes with silver perchlorate or copper(I) perchlorate. Incompatible with metal perc

InChI:InChI=1/C4H8OS/c1-3-6-4-2-5-1/h1-4H2

Upstream product

• 111-48-8 2,2'-thiobis-ethanol 
• 7783-06-4 hydrogen sulfide 
• 107-21-1 ethylene glycol 
• 111-44-4 3-oxa-1,5-dichloropentane 
• 64-17-5 ethanol 
• 505-60-2 bis (2-chloroethyl) sulphide 
• 693-07-2 2-Chloroethyl ethyl sulfide 
• 693-30-1 mustard chlorohydrin 
• 81142-02-1 β-chloroethyl vinyl sulfide 
• 148573-81-3 (Pt(1,4-thioxane)3Cl)(BPh₄) 
• 34270-90-1 2,2'-diiodoethyl ether 
• 75-21-8 oxirane 
• 60-24-2 2-hydroxyethanethiol 
• 609-15-4 ethyl 2-chloro-3-oxo-butyrate 

Downstream Products

• 505-29-3 1,4-Dithiane 
• 130356-10-4 zinc(II)Cl2(1,4-thioxane) 
• 6538-93-8 5,6-dihydro-1,4-oxathiine 
• 107-61-9 1,4-oxathiane-4,4-dioxide 
• 98019-94-4 2,3-dichloro-[1,4]oxathiane 
• 85-47-2 1-naphthalenesulfonic acid 
• 708257-15-2 4-imino-1,4λ⁶-oxathiane 4-oxide 

Relevant articles and documents

Reactions of bielectrophiles (ClCH2CH2)2Y with sulfur in basic reducing systems

A simple procedure was developed for preparing bis(β-mercaptoethyl) ether and bis(β-mecraptoethyl) sulfide from commercially available chemicals: elemental sulfur, alkali, and bis(β-chloroethyl) ether or sulfide, based on thiylation with elemental sulfur of these substrates in the aqueous system hydrazine hydrate-alkali, with initial formation of the corresponding polysulfide polymers (thiokols). Their reduction with the system hydrazine hydrate-alkali, followed by acidification of dithiolate anions, yields the corresponding dithiols. Thiokols based on bis(β-chloroethyl) ether are soluble in organic solvents; they were studied by 1H NMR.

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Destruction of chemical warfare agent simulants by air and moisture stable metal NHC complexes

The cooperative effect of both NHC and metal centre has been found to destroy chemical warfare agent (CWA) simulants. Choice of both the metal and NHC is key to these transformations as simple, monodentate N-heterocyclic carbenes in combination with silver or vanadium can promote stoichiometric destruction, whilst bidentate, aryloxide-tethered NHC complexes of silver and alkali metals promote breakdown under mild heating. Iron-NHC complexes generated in situ are competent catalysts for the destruction of each of the three targetted CWA simulants.

Synthesis of cyclic ethers from diols in the presence of copper catalysts

A number of cyclic ethers, namely tetrahydrofuran, 2,5-dimethyltetrahydrofuran, tetrahydropyran, 1,4-dioxane, oxepane, oxocane, and 1,4-oxathiane, have been synthesized in high yields by intramolecular dehydration of diols in the presence of copper-based catalysts.