15981-64-3Relevant academic research and scientific papers
Microwave-assisted ribosylation of modified heterocyclic bases by Vorbrueggen method
Nikolaus, Nadja V.,Bozilovic, Jelena,Engels, Joachim W.
, p. 889 - 892 (2007)
During the last decades the nucleoside synthesis has proven to be important. The modified silyl-Hilbert-Johnson nucleoside synthesis modified by Vorbrueggen is one of the most often used methods. We have studied N-glycosilation of modifieded heterocyclic bases by Vorbrueggen method with microwave irradiation and we were able to shorten the reaction time and obtain higher yields. The method was demonstrated by fluoroquinolone and purine. Copyright Taylor & Francis Group, LLC.
