159811-30-0 Usage
Description
Toluene-4-sulfonic acid 5-(2,4-difluoro-phenyl)-5-[1,2,4]triazol-1-ylMethyl-tetrahydro-furan-3-ylMethyl is a complex organic compound characterized by its unique molecular structure. It is derived from toluene-4-sulfonic acid and features a 2,4-difluoro-phenyl group, a 1,2,4-triazol-1-ylmethyl group, and a tetrahydro-furan-3-ylmethyl moiety. Toluene-4-sulfonic acid 5-(2,4-difluoro-phenyl)-5-[1,2,4]triazol-1-ylMethyl-tetrahydro-furan-3-ylMethyl is likely to have specific chemical and biological properties due to its intricate structure, making it a potential candidate for various applications in different industries.
Uses
Used in Pharmaceutical Industry:
Toluene-4-sulfonic acid 5-(2,4-difluoro-phenyl)-5-[1,2,4]triazol-1-ylMethyl-tetrahydro-furan-3-ylMethyl is used as an intermediate compound for the synthesis of various pharmaceuticals. Its unique structure may provide specific biological activities or enhance the efficacy of certain drugs, making it a valuable component in the development of new medications.
Used in Chemical Research:
In the field of chemical research, this compound can be used as a research tool to study the properties and reactivity of complex organic molecules. Its synthesis and modification can provide insights into the development of new chemical reactions and the design of novel molecular structures.
Used in Posaconazole Production:
Toluene-4-sulfonic acid 5-(2,4-difluoro-phenyl)-5-[1,2,4]triazol-1-ylMethyl-tetrahydro-furan-3-ylMethyl is used as an impurity in the production of Posaconazole (P689600), an orally active triazole antifungal. As an impurity, it may be present in small amounts during the manufacturing process, and its identification and control are essential for ensuring the quality and safety of the final product.
Check Digit Verification of cas no
The CAS Registry Mumber 159811-30-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,9,8,1 and 1 respectively; the second part has 2 digits, 3 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 159811-30:
(8*1)+(7*5)+(6*9)+(5*8)+(4*1)+(3*1)+(2*3)+(1*0)=150
150 % 10 = 0
So 159811-30-0 is a valid CAS Registry Number.
159811-30-0Relevant articles and documents
HIGHLY STEREOSELECTIVE ACCESS TO NOVEL 2,2,4-TRISUBSTITUTED TETRAHYDROFURANS BY HALOCYCLIZATION: PRACTICAL CHEMOENZYMATIC SYNTHESIS OF SCH 51048, A BROAD-SPECTRUM ORALLY ACTIVE ANTIFUNGAL AGENT
Saksena, Anil K.,Girijavallabhan, Viyyoor M.,Lovey, Raymond G.,Pike, Russell E.,Wang, Haiyan,et al.
, p. 1787 - 1790 (1995)
A convenient synthesis of (-)-(2R)-cis-tosylate 2 is reported via stereoselective 5-exo iodocyclization of the optically active 2,2-disubstituted olefin 9a.Enzymatic desymmetrization of the homoallylic diol 4 with Novo SP435 allowed optimal pro-(S) selectivity to provide the desired (-)-(S)-monoacetate 9a.Under the irreversible reaction conditions, the presence of a bulky aryl substituent on the 2,2-disubstituted olefin seems to determine stereochemical outcome of these halocyclizations.
