1598377-40-2Relevant academic research and scientific papers
Exploring the water-binding pocket of the type II dehydroquinase enzyme in the structure-based design of inhibitors
Blanco, Beatriz,Sedes, Antía,Peón, Antonio,Otero, José M.,Van Raaij, Mark J.,Thompson, Paul,Hawkins, Alastair R.,González-Bello, Concepción
, p. 3494 - 3510 (2014/05/20)
Structural and computational studies to explore the WAT1 binding pocket in the structure-based design of inhibitors against the type II dehydroquinase (DHQ2) enzyme are reported. The crystal structures of DHQ2 from M. tuberculosis in complex with four of
