1598382-74-1

Basic information

• Product Name: (4-chloro-3-fluoro-phenyl)-carbamic acid (S)-2,2,2-trifluoro-1-[(R)-2-(3-trifluoromethyl-phenyl)-morpholin-4-ylmethyl]-ethyl ester
• Synonyms: (4-chloro-3-fluoro-phenyl)-carbamic acid (S)-2,2,2-trifluoro-1-[(R)-2-(3-trifluoromethyl-phenyl)-morpholin-4-ylmethyl]-ethyl ester
• CAS NO: 1598382-74-1
• Molecular Weight: 514.827
• Mol File: 1598382-74-1.mol

Chemical Properties

• CAS DataBase Reference: (4-chloro-3-fluoro-phenyl)-carbamic acid (S)-2,2,2-trifluoro-1-[(R)-2-(3-trifluoromethyl-phenyl)-morpholin-4-ylmethyl]-ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (4-chloro-3-fluoro-phenyl)-carbamic acid (S)-2,2,2-trifluoro-1-[(R)-2-(3-trifluoromethyl-phenyl)-morpholin-4-ylmethyl]-ethyl ester(1598382-74-1)
• EPA Substance Registry System: (4-chloro-3-fluoro-phenyl)-carbamic acid (S)-2,2,2-trifluoro-1-[(R)-2-(3-trifluoromethyl-phenyl)-morpholin-4-ylmethyl]-ethyl ester(1598382-74-1)

Safety Data

• Hazardous Substances Data: 1598382-74-1(Hazardous Substances Data)

Upstream product

• 51163-28-1 1-chloro-2-fluoro-4-isocyanatobenzene 
• 1598382-73-0 (S)-1,1,1-trifluoro-3-((R)-2-(3-(trifluoromethyl)phenyl)morpholino)propan-2-ol 
• 1598382-71-8 (S)-1,1,1-trifluoro-3-[(R)-2-(4-fluoro-3-trifluoromethyl-phenyl)-morpholin-4-yl]-propan-2-ol 

Relevant articles and documents

SUBSTITUTED PHENYLCARBAMATE COMPOUNDS

The invention is concerned with the compounds of formula (I): and pharmaceutically acceptable salts thereof, wherein Y, R1, R2 and R3 are defined in the detailed description and claims. In addition, the present invention relates to methods of manufacturing and using the compounds of formula (I) as well as pharmaceutical compositions containing such compounds. The compounds of formula (I) are antagonists of the TRPA1 channel and may be useful in treating inflammatory diseases and disorders associated with that channel.