159879-42-2Relevant academic research and scientific papers
Analysis of structure-activity relationships for the 'B-region' of N-(3-acyloxy-2-benzylpropyl)-N′-[4-(methylsulfonylamino)benzyl]thiourea analogues as vanilloid receptor antagonists: Discovery of an N-hydroxythiourea analogue with potent analgesic activi
Lee, Jeewoo,Kang, Sang-Uk,Choi, Hyun-Kyung,Lee, Jiyoun,Lim, Ju-Ok,Kil, Min-Jung,Jin, Mi-Kyung,Kim, Kang-Pil,Sung, Jong-Hyuk,Chung, Suk-Jae,Ha, Hee-Jin,Kim, Young-Ho,Pearce, Larry V.,Tran, Richard,Lundberg, Daniel J.,Wang, Yun,Toth, Attila,Blumberg, Peter M.
, p. 2291 - 2297 (2007/10/03)
The structural modifications on the B-region of the potent and high affinity vanilloid receptor (VR1) lead ligand N-(3-acyloxy-2-benzylpropyl)- N′-[4-(methylsulfonylamino)benzyl]thiourea were investigated by the replacement of the thiourea with
The Use of N,O-bis(tert-Butoxycarbonyl)-hydroxylamine in the Synthesis of N-Hydroxylamines and Hydroxamic Acids
Staszak, Michael A.,Doecke, Christopher W.
, p. 6021 - 6024 (2007/10/02)
N,O-bis(tert-butoxycarbonyl)-hydroxylamine has been used in the synthesis of 5-lipoxygenase inhibitor LY280810.In addition, this reagent utilized to synthesize a number of other hydroxylamine and hydroxamic acid derivatives in high yields.
