1599425-03-2Relevant academic research and scientific papers
Constrained TRPV1 agonists synthesized via silver-mediated intramolecular azo-methine ylide cycloaddition of α-iminoamides
Painter, Thomas O.,Kaszas, Krisztian,Gross, Jacklyn,Douglas, Justin T.,Day, Victor W.,Iadarola, Michael J.,Santini, Conrad
, p. 963 - 968 (2014/02/14)
As part of an effort to identify agonists of TRPV1, a peripheral sensory nerve ion channel, high throughput screening of the NIH Small Molecule Repository (SMR) collection identified MLS002174161, a pentacyclic benzodiazepine. A synthesis effort was initi
