1599458-33-9Relevant academic research and scientific papers
Metal-free alkynylation of α-C-H bonds of ethers with ethynylbenziodoxolones
Zhang, Ruo-Yi,Xi, Long-Yi,Zhang, Lei,Liang, Shuai,Chen, Shan-Yong,Yu, Xiao-Qi
, p. 54349 - 54353 (2015/02/02)
A metal-free direct alkylation of C-H bonds adjacent to an oxygen or nitrogen atom was developed. This reaction occurred between saturated heterocycles and ethynylbenziodoxolones under mild conditions. A series of 2-alkynyl cyclic alkanes that contain oxygen or nitrogen atoms were prepared in moderate to good yields. This journal is
KOAc-promoted alkynylation of α-C-H bonds of ethers with alkynyl bromides under transition-metal-free conditions
Zhang, Jiajun,Li, Pinhua,Wang, Lei
, p. 2969 - 2978 (2014/05/06)
A novel KOAc-promoted α-position C-H activation and alkynylation of ethers with alkynyl bromides to 2-alkynyl ethers has been developed under transition-metal-free and simple reaction conditions. In addition, this methodology can also be extended to the vinylation of ethers with vinyl bromides in excellent regio- and stereo-selectivity. A wide range of direct C(sp)-C(sp3) and C(sp2)-C(sp3) bonds has been formed through this protocol, which offers a new and alternative route. This journal is the Partner Organisations 2014.
