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Upstream product

• 120-72-9 indole 
• 1842-38-2 dibenzyl selenide 
• 1482-82-2 dibenzyl diselenide 

Relevant academic research and scientific papers

A solvent- and metal-free synthesis of 3-chacogenyl-indoles employing DMSO/I2 as an eco-friendly catalytic oxidation system

Herein, we describe a solvent- and metal-free method for the synthesis of 3-chalcogenyl-indoles from indoles and diorganyl dichalcogenides using an equivalent amount of DMSO as an oxidant, under catalysis by molecular iodine. This mild and eco-friendly ap

Metal- and photocatalyst-free synthesis of 3-selenylindoles and asymmetric diarylselenides promoted by visible light

A novel and sustainable procedure was developed for the synthesis of 3-selenylindoles employing diorganyl diselenides and indoles or electron-rich arenes as starting materials. Visible blue light was used to promote the reaction without employing transiti

Convenient synthesis of selenyl-indoles via iodide ion-catalyzed electrochemical C-H selenation

Reported herein is a transition metal- and oxidant-free method for the synthesis of selenyl heteroarenes with diselenides through iodide ion-catalyzed electrolytic selenation. This direct C(sp2)-H selenation strategy, with reduced environmental

Rose Bengal catalysed photo-induced selenylation of indoles, imidazoles and arenes: A metal free approach

In this report, the highly efficient Rose Bengal-catalysed C(sp2)-H selenylation of indoles, imidazoles and arenes was achieved using a half molar equiv. of diorganoyl diselenides. This metal-free, photo-induced protocol resulted in selenylated

NaBr mediated regioselective synthesis of 3-Selanylindoles

A convenient NaBr mediated procedure is developed for the preparation of 3-selanylindoles from indoles and diselenides. In this protocol, NaBr is first oxidized by mCPBA into molecular bromine, which reacts with diselenide to form RSeBr. The in situ generated active electrophilic selenium species, then reacts with indoles, affording a series of 3-selanylindoles with high regioselectivity and in moderate to good yields.

Selective synthesis of 3-Selanylindoles from Indoles and Diselenides using IK/mCPBA system

In the presence of a catalytic amount of KI combined with oxidant mCPBA, a convenient catalytic procedure is developed for the preparation of 3-selanylindoles from indoles and diselenides. In this protocol, KI is first oxidized by mCPBA into hypoiodous acid, which reacts with diselenide to cleave Se-Se bond. The in situ generated active electrophilic selenium species then reacts with indole, affording 3-selanylindole via an electrophilic substitution mechanism. This catalytic selenation of indoles has mild reaction conditions and is a simple procedure, which extends the synthetic application of KI in organic synthesis.

Iodine-promoted selective 3-selanylation and 3-sulfenylation of indoles with dichalcogenides under mild conditions

A simple method was developed for the synthesis of 3-chalcogen indoles via iodine-promoted direct 3-selanyl- and 3-sulfenylation of indoles with dichalcogenides. The reaction was carried out smoothly in EtOH under air at room temperature, selectively givi

Synthesis of 3-Selenylindoles under Ecofriendly Conditions

The preparation of biologically relevant 3-selenylindoles by a greener protocol by using a catalytic amount of K2CO3 and ethanol as a biosolvent in a system open to air was explored. Through this easy approach, 3-selenylindoles with