1599466-83-7 Usage
Uses
Used in Pharmaceutical Industry:
Methanesulfonato(2-dicyclohexylphosphino-3,6-dimethoxy-2',4',6'-tri-i-propyl-1,1'-biphenyl)(2'-methylamino-1,1'-biphenyl-2-yl)palladium(II) is used as a catalyst in the synthesis of complex pharmaceutical compounds. Its stability and efficiency in cross-coupling reactions make it an ideal choice for the production of various drug molecules, contributing to the development of new and improved medications.
Used in Chemical Synthesis:
In the field of chemical synthesis, Methanesulfonato(2-dicyclohexylphosphino-3,6-dimethoxy-2',4',6'-tri-i-propyl-1,1'-biphenyl)(2'-methylamino-1,1'-biphenyl-2-yl)palladium(II) is utilized as a catalyst for cross-coupling reactions, enabling the formation of carbon-carbon and carbon-heteroatom bonds. This is crucial for the synthesis of various organic compounds, including those with potential applications in materials science, agrochemistry, and other industries.
Used in Research and Development:
Methanesulfonato(2-dicyclohexylphosphino-3,6-dimethoxy-2',4',6'-tri-i-propyl-1,1'-biphenyl)(2'-methylamino-1,1'-biphenyl-2-yl)palladium(II) is employed as a catalyst in research and development laboratories. Its stability and efficiency in cross-coupling reactions make it a valuable tool for the synthesis of novel compounds and the exploration of new reaction pathways, driving innovation in the field of chemistry.
Reactions
Catalyst used for the N-arylation of amines.
Check Digit Verification of cas no
The CAS Registry Mumber 1599466-83-7 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,5,9,9,4,6 and 6 respectively; the second part has 2 digits, 8 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1599466-83:
(9*1)+(8*5)+(7*9)+(6*9)+(5*4)+(4*6)+(3*6)+(2*8)+(1*3)=247
247 % 10 = 7
So 1599466-83-7 is a valid CAS Registry Number.
1599466-83-7Relevant academic research and scientific papers
N-substituted 2-aminobiphenylpalladium methanesulfonate precatalysts and their use in C-C and C-N cross-couplings
Bruno, Nicholas C.,Niljianskul, Nootaree,Buchwald, Stephen L.
, p. 4161 - 4166 (2014/05/20)
A series of phosphine-ligated palladium precatalysts based on N-methyl- and N-phenyl-2-aminobiphenyl have been developed. Substitution at the nitrogen center prevents the presence of traces of aminobiphenyls that contain a free -NH2 group from contaminating cross-coupling products. These precatalysts produce N-substituted carbazoles upon activation, which cannot consume starting materials. These precatalysts were efficiently generated from 2-aminobiphenyl with minimal purification and found to be highly effective in Suzuki-Miyaura and C-N cross-coupling reactions.
