15995-50-3

Usage

Uses

Used in Medical Research:
N-Phenyl-2-aminonorbornane is used as a research compound for its structural similarity to amphetamines, which may provide insights into the development of new analgesic drugs or understanding the mechanisms of pain relief.
Used in Scientific Research:
N-Phenyl-2-aminonorbornane is used as a model compound in scientific studies to explore the properties and behavior of complex organic molecules, particularly those with potential applications in the pharmaceutical industry.

Upstream product

• 39105-82-3 exo-norbornyldichloroborane 
• 622-37-7 Phenyl azide 
• 498-66-8 norborn-2-ene 
• 62-53-3 aniline 
• 7242-92-4 exo-2-aminonorbornane 
• 12082-05-2 (η6-fluorobenzene)tricarbonylchromium 
• 107440-80-2 Ir(PEt₃)2(C₂H₄)2Cl 
• 279-23-2 norbornene 
• 98-95-3 nitrobenzene 
• 108-86-1 bromobenzene 

Relevant academic research and scientific papers

Inter- and intramolecular hydroamination of unactivated alkenes catalysed by a combination of copper and silver salts: The unveiling of a Bronstedt acid catalysis

The combined use of a copper halide, a silver salt and a phosphane ligand was applied for the catalysis of inter- and intramolecular hydroamination of alkenes. The reactions of unactivated olefins with nitrogen substrates were investigated. Mechanistic investigations demonstrated that the catalytic system generated a Bronsted acid which appeared to be the prominent catalytic species. Copyright

An unusual peroxide-mediated amination of cycloalkanes with nitroarenes

A direct amination of simple cycloalkanes with nitroarenes mediated by peroxides has been discovered. Various secondary arylamines were obtained efficiently from cycloalkanes. The reaction tolerates a wide range of functionalities as well as aqueous condi

HI-catalyzed hydroamination and hydroarylation of alkenes

Aromatic amines react with alkenes in the presence of catalytic amounts of aqueous HI to give mixtures ef the corresponding hydroamination and hydroarylation products. While the hydroamination reaction is the preferred pathway for aliphatic alkenes, the h

Intermolecular hydroamination and hydroarylation reactions of alkenes in ionic liquids

Intermolecular hydroamination or hydroarylation reactions of norbornene and cyclohexadiene performed with catalytic amounts of Br?nsted or Lewis acid in ionic liquids were found to provide higher selectivity and yields than those performed in classical organic solvents. The ionic liquid increases the acidity of the media and stabilizes ionic intermediates through the formation of supramolecular aggregates.

Efficient C-N bond formations catalyzed by a proton-exchanged montmorillonite as a heterogeneous Bronsted acid

Nucleophilic addition of sulfonamides and carboxamides to simple alkenes proceeded smoothly using a proton-exchanged montmorillonite catalyst. The spent catalyst was recovered easily from the reaction mixture and was reusable at least five times without any loss of activity. The unique acidity of the proton-exchanged montmorillonite (H-mont) catalyst was found to be applicable to additional reactions: substitution of hydroxyl groups of alcohols with amides and anilines.

Proton-catalyzed hydroamination and hydroarylation reactions of anilines and alkenes: A dramatic effect of counteranions on reaction efficiency

The anilinium salt, [PhNH3][B(C6F5)4], has been identified as a catalyst for the hydroamination and hydroarylation of several different types of alkenes with anilines. The weakly coordinating counterion of this

Catalytic hydroamination of alkynes and norbornene with neutral and cationic tantalum imido complexes

(Matrix Presented) Several tantalum imido complexes have been synthesized and shown to efficiently catalyze the hydroamination of internal and terminal alkynes. An unusual hydroamination/hydroarylation reaction of norbornene catalyzed by a highly electrop

TiCl4-catalyzed intermolecular hydroamination reactions of norbornene

(Matrix Presented) An intermolecular hydroamination reaction of norbornene is presented that uses catalytic amounts of user-friendly TiCl4 and tolerates a variety of functional groups. In addition, a secondary amine is converted using this meth

Rhodium-catalysed hydroamination-hydroxylation of norbornene with aniline, toluidines or diphenylamine

The condensation of aniline, toluidines or diphenylamine with norbornene tetrahydrofuran is promoted by a system generated from Lin-Bu, ArNH2 and 2>.Aniline and m- and p-toluidines lead to a mixture of hydroamination and hydroarylation produ

Unexpected Catalytic and Stereoselective Hydroarylation of Norbornene During Attempted Rhodium-catalysed Hydroamination of Norbornene with Aniline or Diphenylamine

The reaction of aniline (or diphenylamine) with norbornene in the presence of a catalytic system generated from 2> and PhNHLi (or Ph2NLi) results in hydroarylation to yield 2-(2-aminophenyl)norbornane .