1599529-59-5

Basic information

• Product Name: (4-chloro-2-methoxy-3-(4-(trifluoromethyl)benzyl)quinoline-6-yl)(2,4-dimethyloxazol-5-yl)methanol
• Synonyms: (4-chloro-2-methoxy-3-(4-(trifluoromethyl)benzyl)quinoline-6-yl)(2,4-dimethyloxazol-5-yl)methanol
• CAS NO: 1599529-59-5
• Molecular Weight: 476.883
• Mol File: 1599529-59-5.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: (4-chloro-2-methoxy-3-(4-(trifluoromethyl)benzyl)quinoline-6-yl)(2,4-dimethyloxazol-5-yl)methanol(CAS DataBase Reference)
• NIST Chemistry Reference: (4-chloro-2-methoxy-3-(4-(trifluoromethyl)benzyl)quinoline-6-yl)(2,4-dimethyloxazol-5-yl)methanol(1599529-59-5)
• EPA Substance Registry System: (4-chloro-2-methoxy-3-(4-(trifluoromethyl)benzyl)quinoline-6-yl)(2,4-dimethyloxazol-5-yl)methanol(1599529-59-5)

Safety Data

• Hazardous Substances Data: 1599529-59-5(Hazardous Substances Data)

Upstream product

• 1599529-50-6 6-bromo-4-chloro-2-methoxy-3-(4-(trifluoromethyl)benzyl)quinoline 
• 69062-86-8 2,4-dimethyloxazole-5-carbaldehyde 
• 1599529-49-3 6-bromo-2,4-dichloro-3-(4-(trifluoromethyl)benzyl)quinoline 
• 683215-73-8 2-(4-(trifluoromethyl)benzyl)malonic acid 
• 923977-13-3 2,2-dimethyl-5-(4-trifluoromethyl-benzyl)-[1,3]dioxane-4,6-dione 
• 455-19-6 4-Trifluoromethylbenzaldehyde 

Downstream Products

• 1599531-53-9 (4-chloro-2-methoxy-3-(4-(trifluoromethyl)benzyl)quinolin-6-yl)(2,4-dimethyloxazol-5-yl)(1-methyl-1H-1,2,3-triazol-5-yl)methanol 
• 1599529-60-8 (4-chloro-2-methoxy-3-(4-(trifluoromethyl)benzyl)quinolin-6-yl)(2,4-dimethyloxazol-5-yl)methanone 

Relevant articles and documents

ALKYL LINKED QUINOLINYL MODULATORS OF RORγt

The present invention comprises compounds of Formula I. wherein: R1, R2, R3, R4, R5, R6, R7, R8, and R9 are defined in the specification. The invention also comprises a method of treating or ameliorating a syndrome, disorder or disease, wherein said syndrome, disorder or disease is rheumatoid arthritis or psoriasis. The invention also comprises a method of modulating RORγt activity in a mammal by administration of a therapeutically effective amount of at least one compound of claim 1.

SECONDARY ALCOHOL QUINOLINYL MODULATORS OF RORyt

The present invention comprises compounds of Formula I. wherein: R1, R2, R3, R4, R5, R6, R7, R8, and R9 are defined in the specification. The invention also comprises a method of treating or ameliorating a syndrome, disorder or disease, wherein said syndrome, disorder or disease is rheumatoid arthritis or psoriasis. The invention also comprises a method of modulating RORγt activity in a mammal by administration of a therapeutically effective amount of at least one compound of claim 1.

SECONDARY ALCOHOL QUINOLINYL MODULATORS OF RORyt

The present invention comprises compounds of Formula I. Formula I wherein: R1, R2, R3, R4, R5, R6, R7, R8, and R9 are defined in the specification. The invention also comprises a method of treating or ameliorating a syndrome, disorder or disease, wherein said syndrome, disorder or disease is rheumatoid arthritis or psoriasis. The invention also comprises a method of modulating RORγt activity in a mammal by administration of a therapeutically effective amount of at least one compound of claim 1.