159956-91-9Relevant academic research and scientific papers
Enantioselective synthesis of γ-hydroxysilanes, 1,3-diols and cyclopropanes by reaction of a chiral epoxide with a racemic α-silyl organolithium reagent
Corey,Chen, Zhuoliang
, p. 8731 - 8734 (2007/10/02)
The racemic α-silyl organolithium reagents 2a and 2b react with (R)-styrene oxide enantioselectively to produce the chiral γ-hydroxysilanes 3a and 3b, respectively. The chiral 1,3-diol 4 and cyclopropane 7 are readily obtained in enantiomerically pure form from these γ-hydroxysilanes.
