159990-12-2

Basic information

• Product Name: Boc-beta-(S)-4-methoxyphenylalanine
• Synonyms: (S)-BOC-4-METHOXY-BERA-PHE-OH;(S)-Boc-4-methoxy-β-Phe-OH;Boc-beta-(S)-4-methoxyphenylalanine;(S)-BOC-4-METHOXY-SS-PHE-OH ;Boc-b-Phe(4-OMe)-OH;(S)-3-(Boc-amino)-3-(4-methoxyphenyl)propionic acid, Boc-4-methoxy-D-β-phenylalanine, Boc-O-methyl-D-β-tyrosine, Boc-D-β-Tyr(Me)-OH;(S)-3-((tert-Butoxycarbonyl)aMino)-3-(4-Methoxyphenyl)propanoic acid;Boc-4-Methoxy-L-b-phenylalanine
• CAS NO: 159990-12-2
• Molecular Formula: C₁₅H₂₁NO₅
• Molecular Weight: 295.333
• EINECS: 200-258-5
• Mol File: 159990-12-2.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 463.2 °C at 760 mmHg
• Flash Point: 233.9 °C
• Appearance: /
• Density: 1.167 g/cm³
• Vapor Pressure: 2.23E-09mmHg at 25°C
• Refractive Index: 1.522
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 4.38±0.10(Predicted)
• CAS DataBase Reference: Boc-beta-(S)-4-methoxyphenylalanine(CAS DataBase Reference)
• NIST Chemistry Reference: Boc-beta-(S)-4-methoxyphenylalanine(159990-12-2)
• EPA Substance Registry System: Boc-beta-(S)-4-methoxyphenylalanine(159990-12-2)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 159990-12-2(Hazardous Substances Data)

Usage

Uses

(S)-3-((tert-Butoxycarbonyl)amino)-3-(4-methoxyphenyl)propanoic Acid is used as a reactant in the preparation of carnosine derivatives as selective and efficient sequestering agents of cytotoxic reactive carbonyl species.

InChI:InChI=1/C15H21NO5/c1-15(2,3)21-14(19)16-12(9-13(17)18)10-5-7-11(20-4)8-6-10/h5-8,12H,9H2,1-4H3,(H,16,19)(H,17,18)/t12-/m0/s1

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 131690-56-7 (S)-β-amino-β-(4-methoxyphenyl)propionic acid 
• 159990-11-1 (R)-2-tert-butoxycarbonylamino-1-methanesulfonyloxy-2-(4-methoxyphenyl)ethane 
• 193073-85-7 methyl (R)-2-((tert-butoxycarbonyl)amino)-2-(4-methoxyphenyl)acetate 
• 159848-75-6 (S)-3-(N-terc-butoxycarbonylamine)-3-(4-methoxyphenyl)propanenitrile 
• 159848-74-5 1,1-dimethylethyl (R)-N-[2-hydroxy-1-(4-methoxyphenyl)-ethyl]carbamate 

Downstream Products

• 159848-76-7 methyl (+)-(3S)-3-amino-3-(4-methoxyphenyl)propanoate 
• 159848-82-5 methyl (3S,3'S)-3-<3'-tert-butyldimethylsiloxy-3'-(4-methoxyphenyl)propylamino>-3-(4-methoxyphenyl)propionate 
• 159848-94-9 methyl (3S,3S')-3-<3'-tert-butoxycarbonylamino-3'-(4-methoxyphenyl)propylamino>-3-(4-methoxyphenyl)propionate 
• 159848-84-7 [(S)-3-(tert-Butyl-dimethyl-silanyloxy)-3-(4-methoxy-phenyl)-propyl]-[(S)-3-hydroxy-1-(4-methoxy-phenyl)-propyl]-carbamic acid tert-butyl ester 
• 159848-96-1 (3S,3S')-3--3-(4-methoxyphenyl)-1-propanol 
• 159848-83-6 methyl (3S,3'S)-3--3-(4-methoxyphenyl)propionate 
• 159848-86-9 (3S,3'S)-3--3-(4-methoxyphenyl)-1-(2,2,2-trichloroethoxycarbonyloxy)propane 
• 159848-95-0 methyl (3S,3S')-3--3-(4-methoxyphenyl)propionate 
• 159848-87-0 (3S,3'S)-3-<3'-acetoxy-N-tert-butoxycarbonyl-3'-(4-methoxyphenyl)propylamino>-3-(4-methoxyphenyl)-1-(2,2,2-trichloroethoxycarbonyloxy)propane 
• 159848-97-2 (3S,3S')-3--3-(4-methoxyphenyl)-1-(2,2,2-trichloroethoxycarbonyloxy)propane 
• 159848-85-8 (3S,3'S)-3--3-(4-methoxyphenyl)-1-(2,2,2-trichloroethoxycarbonyloxy)propane 
• 96363-21-2 methyl (S)-3-tert-butoxycarbonylamino-3-(4-methoxyphenyl)propionate 

Relevant articles and documents

Total Synthesis of 2'-Deoxymugineic Acid and Nicotianamine

Steroselective total synthesis of the unique phytosiderophores, 2'-deoxymugineic acid (4) and nicotianamine (5), has been achieved from the β-tyrosine derivative 21 using its aryl groups as the carboxyl synthon.