160030-77-3

Upstream product

• 206866-34-4 [4-Allyl-4-(2-methoxymethoxy-ethyl)-cyclohexa-1,5-dienyloxy]-tert-butyl-dimethyl-silane 

Downstream Products

• 1351666-61-9 methyl 5-(2-(methoxymethoxy)ethyl)-2-oxo-5-(2-propenyl)-3-cyclohexene-1-carboxylate 
• 206866-34-4 [4-Allyl-4-(2-methoxymethoxy-ethyl)-cyclohexa-1,5-dienyloxy]-tert-butyl-dimethyl-silane 
• 206866-11-7 [4-Allyl-4-(2-methoxymethoxy-ethyl)-cyclohexa-1,5-dienyloxy]-trimethyl-silane 

Relevant academic research and scientific papers

Some aspects of palladium-catalyzed cycloalkenylation: Developments of environmentally benign catalytic conditions and demonstration of tandem cycloalkenylation

The influences of catalysts, substituent groups, and solvents on the palladium-catalyzed cycloalkenylation of cross-conjugated silyl enol ethers of 2-tert-butyldimethylsiloxy-5-(2-propenyl)-1,3-cyclohexadiene derivatives have been investigated. The catalytic reaction proceeded smoothly, even in aqueous media. The product ratios were influenced by the structure of substrates as well as solvents. In addition, it was found that the reaction is applicable to a tandem cyclization for the construction of cedrane skeleton.

INOC REACTION IN GIBBERELLIN SYNTHESIS - A PRACTICAL SYNTHESIS OF THE KEY INTERMEDIATE FOR GIBBERELLIN A12

The isoxazoline (10), a possible key intermediate for gibberellin A12 (1), has been synthesized in 91percent yield by means of intramolecular nitrile oxide cycloaddition (INOC) reaction of the oxime (9).

Simple design for the construction of complex gibberellin framework - Stereoselective synthesis of a possible key intermediate to GA12 via Pd2+-promoted cycloalkenylation reaction

A successful design for the construction of C20 gibberellin framework has been described. The key features of the synthesis are as follows: (a) Pd2+-promoted cycloalkenylation reaction (6→5) and (b) intramolecular Diels-Alder reaction (4→3).