1600500-92-2Relevant academic research and scientific papers
Zinc-catalyzed direct cyanation of indoles and pyrroles: Nitromethane as a source of a cyano group
Nagase, Yuta,Sugiyama, Tetsuya,Nomiyama, Shota,Yonekura, Kyohei,Tsuchimoto, Teruhisa
, p. 347 - 352 (2014/05/20)
With nitromethane and diphenylsilane (Ph2SiH2), zinc triflate behaves as a Lewis acid catalyst for the cyanation of nitrogen-containing heteroarenes such as indoles and pyrroles. This is the first realization of the Lewis acid-catalyzed direct cyanation of a C(aryl)-H bond with no CN group-containing cyanating agent.
