1600564-84-8

Upstream product

• 1600562-94-4 (1-methyl-1H-imidazol-5-yl)(pyridin-4-yl)methanone 
• 1600563-62-9 (2,4-dichloro-3-phenylquinolin-6-yl)(1-methyl-1H-imidazol-5-yl)(pyridin-4-yl)methanol 
• 683-60-3 sodium isopropylate 
• 76-05-1 trifluoroacetic acid 
• 452349-62-1 methyl 5-bromo-2-(2-phenylacetamido)benzoate 
• 909365-96-4 6-bromo-4-hydroxy-3-phenylquinolin-2(1H)-one 
• 1600562-81-9 6-bromo-2,4-dichloro-3-phenylquinoline 
• 52727-57-8 5-bromo-2-aminobenzoic acid methyl ester 
• 100377-32-0 N-methyl-N-methoxyisonicotinamide 
• 55-22-1 pyridine-4-carboxylic acid 
• 103-80-0 phenylacetyl chloride 

Relevant academic research and scientific papers

HETEROARYL LINKED QUINOLINYL MODULATORS OF RORyt

The present invention comprises compounds of Formula I. wherein: R1, R2, R3, R4, R5, R6, R7, R8, and R9 are defined in the specification. The invention also comprises a method of treating or ameliorating a syndrome, disorder or disease, wherein said syndrome, disorder or disease is rheumatoid arthritis or psoriasis. The invention also comprises a method of modulating RORγt activity in a mammal by administration of a therapeutically effective amount of at least one compound of claim 1.