160093-50-5Relevant academic research and scientific papers
First synthesis and full characterization of mexiletine N-carbonyloxy β-d-glucuronide
Cavalluzzi, Maria Maddalena,Lentini, Giovanni,Lovece, Angelo,Bruno, Claudio,Catalano, Alessia,Carocci, Alessia,Franchini, Carlo
scheme or table, p. 5265 - 5268 (2010/11/03)
A simple, convergent synthesis of the N-carbonyloxy β-d-glucuronide of mexiletine (sodium salt) in moderate yield is described. The compound is now available as an authentic reference standard for analytical studies, enabling more detailed investigation on the metabolism of mexiletine.
