16012-55-8 Usage
Uses
L-BMAA hydrochloride has been used as a standard to compare all the samples in the analysis of β-N-methylamino-l-alanine (BMAA) isomers in desert crust material. It has also been used as an additive with f/2+Si medium?to treat the cells of?Phaeodactylum tricornutum and?Thalassiosira weissflogii?to study its effect on them.
General Description
L-BMAA hydrochloride/β-N-methylamino-l-alanine (BMAA) is a cyanobacterial neurotoxin.
Biochem/physiol Actions
L-BMAA hydrochloride helps to block the addition of heparan sulfate to glypican-1. It possesses unusual glutamate receptor binding properties. It may cause amyotrophic lateral sclerosis/Lou Gehrig′s disease.
Check Digit Verification of cas no
The CAS Registry Mumber 16012-55-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,6,0,1 and 2 respectively; the second part has 2 digits, 5 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 16012-55:
(7*1)+(6*6)+(5*0)+(4*1)+(3*2)+(2*5)+(1*5)=68
68 % 10 = 8
So 16012-55-8 is a valid CAS Registry Number.
16012-55-8Relevant articles and documents
A simple and efficient approach to the synthesis of β-N-methylamino-l- alanine (BMAA)
Arévalo-García, Enzo B.,Colmenares Q., Juan Carlos
, p. 2335 - 2336 (2014/05/06)
A novel, efficient, and straightforward synthesis of β-N-methylamino- l-alanine (BMAA) in two steps starting from l-N,N-dibenzylserine benzyl ester is described. This method, in the light of other syntheses of BMAA, provides benefits such as mild reaction conditions, a simple work-up procedure, good yields, and the retention of the serine stereochemistry.
