160132-71-8

Upstream product

• 583-75-5 4-Bromo-2-methylaniline 
• 870-24-6 2-chloroethanamine hydrochloride 
• 1591-98-6 2-methyl-4-bromophenyl isocyanate 

Downstream Products

• 160132-31-0 1-(4-bromo-2-methylphenyl)imidazolidin-2-one 

Relevant academic research and scientific papers

DGAT1 INHIBITOR AND PREPARATION METHOD AND USE THEREOF

The present invention discloses a novel DGAT1 inhibitor, especially the compound of formula (I) or a pharmaceutically acceptable salt thereof, preparation and pharmaceutical composition thereof, as well as their uses in the preparation of a medicament for the prevention and treatment of Familial hyperchylomicronemia (FCS), obesity, hyperlipoproteinemia or hypertriglyceridemia.

Cyclic urea derivatives, pharmaceutical compositions containing these compounds and processes for preparing them

The invention relates to cyclic urea derivatives of general formula I STR1 wherein Ra, Rb, X and Y are defined as in claim 1, the tautomers, stereoisomers and salts thereof, particularly the physiologically acceptable salts thereof with inorganic or organic acids or bases, which have valuable pharmacological properties, preferably aggregation inhibiting effects, and to drugs containing the compounds and processes for preparing them.