160146-65-6

Upstream product

• 159831-20-6 10-bromoacetyl-11-ethoxycarbonyl-10,11-dihydropyrrolo<1,2-b><1,2,5>benzothiadiazepine 5,5-dioxide 
• 100-46-9 benzylamine 
• 54254-41-0 1-(2-aminobenzenesulfonyl)-1H-pyrrole 
• 160146-64-5 ethyl 10,11-dihydropyrrolo<1,2-b><1,2,5>benzothiadiazepine-11-carboxylate 5,5-dioxide 

Downstream Products

• 160146-67-8 2-benzyl-1,3,4,14b-tetrahydro-2H-pyrazino<2,1-d>pyrolo<1,2-b><1,2,5>benzothiadiazepine 10,10-dioxide 
• 160146-66-7 2-benzyl-1,4-dioxo-1,3,4,14b-tetrahydro-2H-pyrazino<2,1-d>pyrolo<1,2-b><1,2,5>benzothiadiazepine 10,10-dioxide 

Relevant academic research and scientific papers

Heterocycles with a benzothiadiazepine moiety. 2. Synthesis of 2-methyl-1,3,4,14b-tetrahydro-2H-pyrazino[2,1-d]pyrrolo-[1,2-b][1,2,5] benzothiadiazepine 10,10-dioxide (tiaaptazepine)

The synthesis of 2-methyl-1,3,4,14b-tetrahydro-2H-pyrazino[2,1-d]pyrrolo[1,2-b][1,2,5]b enzothiadiazepine 10,10-dioxide (tiaaptazepine), a novel tetracyclic structure strictly related to antidepressant aptazepine, is described starting from 1-(2-aminobenz