1601483-92-4Relevant articles and documents
A novel atom-economic synthesis of functionalized imidazolidines through copper(I)-catalyzed domino three-component coupling and cyclization reactions
Li, Yufeng,Wu, Zhengguang,Shi, Jie,Bu, Hongzhong,Gu, Jiachao,Pan, Yi
supporting information, p. 3134 - 3140 (2014/05/06)
An interesting approach to functionalized imidazolidines is described. These compounds are obtained in a copper(I)-catalyzed domino three-component coupling and cyclization reaction involving two formaldehyde-derived imine units and a terminal alkyne. Alternatively, imidazolidines can be obtained from propargylamines and formaldehyde-derived imines. This strategy provides a straightforward and atom-economic pathway to construct imidazolidines with high yields and benefits from readily available starting materials, convenient one-pot operations.