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16015-75-1

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16015-75-1 Usage

General Description

1-(2,4-DIMETHOXYPHENYL)PIPERAZINE is a chemical compound with the formula C12H18N2O2. It is a derivative of piperazine, a heterocyclic compound commonly used in pharmaceuticals and agrochemicals. This particular compound contains a piperazine ring substituted with a 2,4-dimethoxyphenyl group. It is used in the synthesis of various pharmaceutical agents and may have potential applications in medicinal chemistry. The compound's structure and properties make it a valuable building block for the development of new drugs and bioactive molecules. Additionally, it may have potential use as a research tool in chemical and biological studies.

Check Digit Verification of cas no

The CAS Registry Mumber 16015-75-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,6,0,1 and 5 respectively; the second part has 2 digits, 7 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 16015-75:
(7*1)+(6*6)+(5*0)+(4*1)+(3*5)+(2*7)+(1*5)=81
81 % 10 = 1
So 16015-75-1 is a valid CAS Registry Number.
InChI:InChI=1/C12H18N2O2/c1-15-10-3-4-11(12(9-10)16-2)14-7-5-13-6-8-14/h3-4,9,13H,5-8H2,1-2H3

16015-75-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-(2,4-dimethoxyphenyl)piperazine

1.2 Other means of identification

Product number -
Other names 1-(2,4-dimethoxyphenyl)-piperazine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:16015-75-1 SDS

16015-75-1Relevant articles and documents

Pd-Catalyzed Synthesis of Piperazine Scaffolds under Aerobic and Solvent-Free Conditions

Reilly, Sean W.,Mach, Robert H.

supporting information, p. 5272 - 5275 (2016/10/31)

A facile Pd-catalyzed methodology providing an efficient synthetic route to biologically relevant arylpiperazines under aerobic conditions is reported. Electron donating and sterically hindered aryl chlorides were aminated to afford yields up to 97%, with examples using piperazine as solvent, illustrating an ecofriendly, cost-effective synthesis of these privileged structures.

Synthesis and evaluation of arylpiperazines derivatives of 3,5-dioxo-(2H,4H)-1,2,4-triazine as 5-HT1AR ligands

Kumar, J.S. Dileep,Majo, Vattoly J.,Prabhakaran, Jaya,Mann, J. John

, p. 4759 - 4762 (2015/01/08)

5-HT1AR agonist or partial agonists are established drug candidates for psychiatric and neurological disorders. We have reported the synthesis and evaluation of a series of high affinity 5-HT1AR partial agonist PET imaging agents with greater selectivity over α-1AR. The characteristic of these molecules are 3,5-dioxo-(2H,4H)-1,2,4-triazine skeleton tethered to an arylpiperazine unit through an alkyl side chain. The most potent 5-HT1AR agonistic properties were found to be associated with the molecules bearing C-4 alkyl group as the linker. Therefore development of 3,5-dioxo-(2H,4H)-1,2,4-triazine bearing arylpiperazine derivatives may provide high affinity selective 5-HT1AR ligands. Herein we describe the synthesis and evaluation of the binding properties of a series of arylpiperazine analogues of 3,5-dioxo-(2H,4H)-1,2,4-triazine.

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