16018-49-8

Basic information

• Product Name: 1-(4,6-DIMETHYL-2-PYRIMIDINYL)-3-PHENYLGUANIDINE
• Synonyms: 1-(4,6-DIMETHYL-2-PYRIMIDINYL)-3-PHENYLGUANIDINE;N-(4,6-Dimethyl-2-pyrimidinyl)-N'-phenylguanidine
• CAS NO: 16018-49-8
• Molecular Formula: C₁₃H₁₅N₅
• Molecular Weight: 241.2917
• Mol File: 16018-49-8.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 446.5°C at 760 mmHg
• Flash Point: 223.8°C
• Appearance: /
• Density: 1.21g/cm³
• Vapor Pressure: 3.62E-08mmHg at 25°C
• Refractive Index: 1.634
• CAS DataBase Reference: 1-(4,6-DIMETHYL-2-PYRIMIDINYL)-3-PHENYLGUANIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4,6-DIMETHYL-2-PYRIMIDINYL)-3-PHENYLGUANIDINE(16018-49-8)
• EPA Substance Registry System: 1-(4,6-DIMETHYL-2-PYRIMIDINYL)-3-PHENYLGUANIDINE(16018-49-8)

Safety Data

• Hazardous Substances Data: 16018-49-8(Hazardous Substances Data)

Usage

General Description

1-(4,6-dimethyl-2-pyrimidinyl)-3-phenylguanidine is a chemical compound with the molecular formula C13H16N4. It is commonly used in the production of pharmaceuticals and agrochemicals. 1-(4,6-DIMETHYL-2-PYRIMIDINYL)-3-PHENYLGUANIDINE belongs to the class of guanidines, which are known for their diverse range of biological activities. Specifically, 1-(4,6-dimethyl-2-pyrimidinyl)-3-phenylguanidine has been studied for its potential as an anti-cancer agent and has shown promise in inhibiting the growth of certain types of tumor cells. Additionally, it has been investigated for its potential as a pesticide and has been shown to have insecticidal properties. Overall, this compound has a wide range of potential applications and is of interest to researchers in the fields of medicine and agriculture.

InChI:InChI=1/C13H15N5/c1-9-8-10(2)16-13(15-9)18-12(14)17-11-6-4-3-5-7-11/h3-8H,1-2H3,(H3,14,15,16,17,18)

Upstream product

• 102-02-3 1-phenylbiguanide 
• 123-54-6 acetylacetone 
• 55474-90-3 (4,6-dimethylpyrimidin-2-yl)cyanamide 
• 62-53-3 aniline 

Downstream Products

• 1070270-42-6 (E)-2-[(4,6-dimethylpyrimidin-2-yl)imino]-1-phenylimidazolidin-4-one 
• 1070270-52-8 (E)-methyl 2-{(E)-2-[(4,6-dimethylpyrimidin-2-yl)imino]-5-oxo-3-phenylimidazolidin-4-ylidene}acetate 
• 1314895-23-2 N-[4-(4-bromophenyl)-1-phenyl-1H-imidazol-2-yl]-4,6-dimethylpyrimidin-2-amine 
• 94828-55-4 N'-(4,6-dimethyl-pyrimidin-2-yl)-N-phenyl-N'-(2-chloro-benzenesulphonyl)-guanidine 
• 94828-36-1 N'-(4,6-dimethyl-pyrimidin-2-yl)-N-phenyl-N,N'-bis-(2-chloro-benzenesulphonyl)-guanidine 
• 94828-37-2 N'-(4,6-dimethyl-pyrimidin-2-yl)-N-phenyl-N'-(2,5-dichloro-benzenesulphonyl)-guanidine 

Relevant articles and documents

Arylbiguanides in heterocyclization reactions

The reactions of arylbiguanides with acetyacetone derivatives were used to obtain N-(pyrimidin-2-yl)-N′-arylguanidines, and the reactions with acetoacetic ester derivatives (depending on the structure of the keto esters), N-aryl-N′-(4-oxo-3,4-dihydropyrim