160247-31-4

Upstream product

• 84773-28-4 (R)-2-(methylamino)-2-phenylethanol 
• 141-75-3 butyryl chloride 

Downstream Products

• 774164-27-1 (R)-2-[((S)-2-Benzyl-butyl)-methyl-amino]-2-phenyl-ethanol 
• 160247-34-7 (S)-2-Benzyl-N-((R)-2-hydroxy-1-phenyl-ethyl)-N-methyl-butyramide 
• 160247-33-6 (R)-N-((R)-2-Hydroxy-1-phenyl-ethyl)-2,N-dimethyl-butyramide 

Relevant academic research and scientific papers

Origins of diastereoselectivity in the alkylation of N-substituted lactams and amides derived from optically active aminoalcohols

The origins of diastereoselectivity in the alkylation of lactams 1a and 1b and amides 6a and 6b are discussed. A rigid intermediate in which the pyramidalized amide nitrogen chelated the alkoxide lithium cation is invoked. Further experiments conducted wi

Asymmetric synthesis. XXXIII. Diastereoselective alkylation of N,N-substituted amides

A series of α-substituted amides 3 and 7-9 has been synthesized in enantiomerically pure form by diastereoselective alkylation of N-alkyl phenylglycinol amides 2 and 4-6 respectively. A rigid amide enolate has been postulated to explain the observed diast