1602588-73-7Relevant articles and documents
Synthesis, antitubulin, and antiproliferative sar of c3/c1-substituted tetrahydroisoquinolines
Dohle, Wolfgang,Leese, Mathew P.,Jourdan, Fabrice L.,Major, Meriel R.,Bai, Ruoli,Hamel, Ernest,Ferrandis, Eric,Kasprzyk, Philip G.,Fiore, Ann,Newman, Simon P.,Purohit, Atul,Potter, Barry V. L.
, p. 350 - 370 (2014/04/03)
The syntheses and antiproliferative activities of novel substituted tetrahydroisoquinoline derivatives and their sulfamates are discussed. Biasing of conformational populations through substitution on the tetrahydroisoquinoline core at C1 and C3 has a pro