1602924-18-4

Basic information

• Product Name: (S)-1,1,1-trifluoro-3-[3-(3-methoxyphenyl)-piperidin-1-yl]-propan-2-ol
• Synonyms: (S)-1,1,1-trifluoro-3-[3-(3-methoxyphenyl)-piperidin-1-yl]-propan-2-ol
• CAS NO: 1602924-18-4
• Molecular Weight: 303.325
• Mol File: 1602924-18-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-1,1,1-trifluoro-3-[3-(3-methoxyphenyl)-piperidin-1-yl]-propan-2-ol(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-1,1,1-trifluoro-3-[3-(3-methoxyphenyl)-piperidin-1-yl]-propan-2-ol(1602924-18-4)
• EPA Substance Registry System: (S)-1,1,1-trifluoro-3-[3-(3-methoxyphenyl)-piperidin-1-yl]-propan-2-ol(1602924-18-4)

Safety Data

• Hazardous Substances Data: 1602924-18-4(Hazardous Substances Data)

Upstream product

• 19725-18-9 (+)-3-(3-methoxyphenyl)piperidine hydrochloride 
• 130025-34-2 (S)-2-trifluoromethyl-oxirane 

Downstream Products

• 1602923-62-5 (4-bromophenyl)-carbamic acid (S)-2,2,2-trifluoro-1-[3-(3-methoxyphenyl)-piperidin-1-ylmethyl]-ethyl ester hydrochloride 

Relevant articles and documents

SUBSTITUTED CARBAMATE COMPOUNDS AND THEIR USE AS TRANSIENT RECEPTOR POTENTIAL (TRP) CHANNEL ANTAGONISTS

The invention is concerned with the compounds of formula (I): and pharmaceutically acceptable salts thereof, wherein Y, R1 and R3 are defined in the detailed description and claims. In addition, the present invention relates to methods of manufacturing and using the compounds of formula (I) as well as pharmaceutical compositions containing such compounds. The compounds of formula (I) are antagonists of the TRPA1 channel and may be useful in treating inflammatory diseases and disorders associated with that channel.