1602983-02-7

Basic information

• Product Name: C₂₁H₁₆⁽²⁾HNO₂
• Synonyms: C₂₁H₁₆⁽²⁾HNO₂
• CAS NO: 1602983-02-7
• Molecular Weight: 316.364
• Mol File: 1602983-02-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₁H₁₆⁽²⁾HNO₂(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₁H₁₆⁽²⁾HNO₂(1602983-02-7)
• EPA Substance Registry System: C₂₁H₁₆⁽²⁾HNO₂(1602983-02-7)

Safety Data

• Hazardous Substances Data: 1602983-02-7(Hazardous Substances Data)

Upstream product

• 1602982-98-8 C₂₁H₁₇⁽²⁾H₂NO₂ 
• 38662-32-7 benzylidene-(dideuterio-phenyl-methyl)-amine 
• 15185-02-1 1,1-dideuteriobenzylamine 
• 55-21-0 benzamide 

Relevant articles and documents

Predictably selective (sp3)C-O bond formation through copper catalyzed dehydrogenative coupling: Facile synthesis of dihydro-oxazinone derivatives

An intramolecular dehydrogenative (sp3)C-O bond formation in salicylamides can be initiated by an active Cu/O2 species to generate pharamaceutically relevant dihydro-oxazinones. Experimental findings suggest that stereoelectronic parameters in both coupling partners are controlling factors for site selectivity in bond formation. Mechanistic investigations including isotope labeling, kinetic studies helped to propose a catalytic cycle. The method provides a convenient synthesis of an investigational new medicine CX-614, which has potential in finding treatment for Parkinson's and Alzheimer's diseases.