160335-16-0

Upstream product

• 71596-98-0 (1S,4R)-4,7,7-Trimethyl-3-oxo-2-oxa-bicyclo[2.2.1]heptane-1-carboxylic acid (S)-2,4,4-trimethyl-3-((E)-3-oxo-but-1-enyl)-cyclohex-2-enyl ester 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 71629-15-7 4-(3-Hydroxy-2,6,6-trimethyl-1-cyclohexen-1-yl)-3-buten-2-one 
• 14398-34-6 4-(3-hydroxy-2,6,6-trimethylcyclohex-1-enyl)but-3-en-2-one 

Relevant academic research and scientific papers

Synthesis of (+)-(4S)- and (-)-(4R)11 Z-4-hydroxyretinals and determination of the absolute stereochemistry of a visual pigment chromophore in the bioluminescent squid, Watasenia scintillans

Synthesis of (+)-(4S)- and (-)-(4R)-11Z-4-hydroxyretinals (4-OH-RALs) 1a and 1b was accomplished from (4S)- and (4R)-4-hydroxy-β-ionones, respectively, to determine the absolute configuration of a visual pigment chromophore in Watasenia scintillans. The C

Synthesis of (+)-(4S)- and (-)-(4R)-(11Z)-4-hydroxyretinals and determination of the absolute stereochemistry of a visual pigment chromophore in the firefly squid, Watasenia scintillans

First syntheses of (+)-(4S)- and (-)-(4R)-(11Z)-4-hydroxyretinals (4-OH-RALs) (4a and 4b) were accomplished from (4S)- and (4R)-4-hydroxy-β-ionones, respectively, to determine the absolute configuration of a visual pigment chromophore in Watasenia scintillans, which has been isolated as a new chromophore in the animal kingdom. The CD spectra of the native chromophore and its anti-oxime agreed with those of synthetic (4R)-compounds. Application of the CD exciton chirality method to the p-(dimethylamino)cinnamate of (4R)-4-OH-RAL also established the absolute configuration of the native chromophore as 4b.