160348-61-8

Basic information

• Product Name: 5-(ALLYLOXY)-3-METHYL-1-PHENYL-1H-PYRAZOLE-4-CARBALDEHYDE OXIME
• Synonyms: 5-(ALLYLOXY)-3-METHYL-1-PHENYL-1H-PYRAZOLE-4-CARBALDEHYDE OXIME;(E)-N-{[3-methyl-1-phenyl-5-(prop-2-en-1-yloxy)-1H-pyrazol-4-yl]methylidene}hydroxylamine
• CAS NO: 160348-61-8
• Molecular Formula: C14H15N3O2
• Molecular Weight: 257.29
• Mol File: 160348-61-8.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 427.4±45.0 °C(Predicted)
• Appearance: /
• Density: 1.15±0.1 g/cm3(Predicted)
• PKA: 10.50±0.10(Predicted)
• CAS DataBase Reference: 5-(ALLYLOXY)-3-METHYL-1-PHENYL-1H-PYRAZOLE-4-CARBALDEHYDE OXIME(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(ALLYLOXY)-3-METHYL-1-PHENYL-1H-PYRAZOLE-4-CARBALDEHYDE OXIME(160348-61-8)
• EPA Substance Registry System: 5-(ALLYLOXY)-3-METHYL-1-PHENYL-1H-PYRAZOLE-4-CARBALDEHYDE OXIME(160348-61-8)

Safety Data

• Hazardous Substances Data: 160348-61-8(Hazardous Substances Data)

Upstream product

• 947-95-5 5-chloro-4-formyl-3-methyl-1-phenyl-1H-pyrazole 
• 160348-52-7 5-allyloxy-3-methyl-1-phenylpyrazole-4-carbaldehyde 

Relevant articles and documents

5-Chloropyrazole-4-carbaldehydes as Synthons for Intramolecular 1,3-Dipolar Cycloadditions

A general method is described to transform the readily available title compounds into tri- and tetracyclic heterocycles, first by substituting the chlorine atom by an unsaturated thiolate or alkoxide, and then by modifying the aldehyde function into a 1,3-dipole.As 1,3-dipoles, nitrile oxide, nitrone, nitrile imine, azomethine ylide and azomethine imine groups were generated from the 5-allylsulfanyl-4-formylpyrazole 7, which resulted in intramolecular cycloaddition and formation of the heterocycles shown in Scheme 2.The other pyrazoles 22, 23, 26, 30 and 33 were converted via intramolecular nitrile oxide cycloaddition (INOC) into fused dihydroisoxazoles.A limitation to the method is the Claisen rearrangement which occurs when the allyl ether 26 or the prop-2-ynyl ether 30 is used.