1603829-74-8Relevant academic research and scientific papers
Iron-catalyzed radical oxidative coupling reaction of aryl olefins with 1,3-dithiane
Du, Wenbin,Tian, Lixia,Lai, Junshan,Huo, Xing,Xie, Xingang,She, Xuegong,Tang, Shouchu
, p. 2470 - 2473 (2014)
An alternative method to an iron-catalyzed radical oxidative cross-coupling reaction followed by 2-chloro-1,3-dithiane and aryl olefins for the synthesis of β-chloro substituent 1,3-dithiane products is presented. The described method has the advantage of mildness of the reaction conditions and tolerates a variety of functional groups. Preliminary mechanistic studies have confirmed the first example of a coupling of 1,3-dithiane with unactivated alkenes that proceeds via an iron-catalyzed oxidative radical intermediate along the reaction pathway.
