1603838-15-8Relevant articles and documents
Iridium(I)-catalyzed direct C-H bond alkylation of the C-7 position of indolines with alkenes
Pan, Shiguang,Ryu, Naoto,Shibata, Takanori
, p. 929 - 933 (2014/04/03)
A cationic iridium-catalyzed C-7 alkylation of N-substituted indoline derivatives with various alkenes has been developed. A variety of 7-alkylindolines were obtained in moderate to high yields. This protocol relies on the use of the carbonyl group on the nitrogen atom of indoline as a directing group and it is potentially applicable to the large-scale synthesis of 7-alkylindoles.