1603923-06-3

Upstream product

• 5305-59-9 4-amino-6-chloropyrimidine 
• 179899-07-1 4-fluoro-2-methoxyphenylboronic acid 

Downstream Products

• 1603923-12-1 6-(4-fluoro-2-methoxyphenyl)-N-{4-[(methylsulfanyl)methyl]-6-(trifluoromethyl)pyridin-2-yl}pyrimidin-4-amine 
• 1610462-83-3 N-[6-chloro-4-(chloromethyl)pyridin-2-yl]-6-(4-fluoro-2-methoxyphenyl)pyrimidin-4-amine 
• 1610462-84-4 N-{6-chloro-4-[(methylsulfanyl)methyl]pyridin-2-yl}-6-(4-fluoro-2-methoxyphenyl)pyrimidin-4-amine 
• 1610462-86-6 (rac)-2,2,2-trifluoro-N-{[(2-{[6-(4-fluoro-2-methoxyphenyl)pyrimidin-4-yl]amino}-6-methylpyridin-4-yl)methyl](methyl)-λ⁴-sulfanylidene}acetamide 
• 1610462-75-3 (rac)-6-(4-fluoro-2-methoxyphenyl)-N-{6-methyl-4-[(S-methylsulfonimidoyl)methyl]pyridin-2-yl}pyrimidin-4-amine 
• 1610462-76-4 (R)-6-(4-fluoro-2-methoxyphenyl)-N-{6-methyl-4-[(S-methylsulfonimidoyl)methyl]pyridin-2-yl}pyrimidin-4-amine 
• 1610462-77-5 (S)-6-(4-fluoro-2-methoxyphenyl)-N-{6-methyl-4-[(S-methylsulfonimidoyl)methyl]pyridin-2-yl}pyrimidin-4-amine 
• 1610462-87-7 (rac)-2,2,2-trifluoro-N-[{[2-{[6-(4-fluoro-2-methoxyphenyl)pyrimidin-4-yl]amino}-6-(trifluoromethyl)pyridin-4-yl]methyl}(methyl)-λ⁴-sulfanylidene]acetamide 
• 1610462-78-6 (rac)-6-(4-fluoro-2-methoxyphenyl)-N-{4-[(S-methylsulfonimidoyl)methyl]-6-(trifluoromethyl)pyridin-2yl}pyrimidin-4-amine 
• 1610462-82-2 (2-chloro-6-{[6-(4-fluoro-2-methoxyphenyl)pyrimidin-4-yl]amino}pyridin-4-yl)methanol 
• 1603922-87-7 6-(4-fluoro-2-methoxyphenyl)-N-{6-methyl-4-[(methylsulfonyl)methyl]pyridin-2-yl}pyrimidin-4-amine 
• 1603923-09-6 C₁₉H₁₉FN₄OS 

Relevant academic research and scientific papers

N-(PYRIDIN-2-YL)PYRIMIDIN-4-AMINE DERIVATIVES CONTAINING A SULFONE GROUP

The present invention relates to N-(pyridin-2-yl)pyrimidin-4-amine derivatives containing a sulfone group of general formula (I) as described and defined herein, and methods for their preparation, their use for the treatment and/or prophylaxis of disorder

N-(PYRIDIN-2-YL)PYRIMIDIN-4-AMINE DERIVATIVES CONTAINING A SULFOXIMINE GROUP

The present invention relates to disubstituted N-(pyridin-2-yl)pyrimidin-4-amine derivatives containing a sulfoximine group of general formula (I) as described and defined herein, and methods for their preparation, their use for the treatment and/ or prophylaxis of disorders, in particular of hyper- proliferative disorders and/or virally induced infectious diseases and/or of cardiovascular diseases. The invention further relates to intermediate compounds useful in the preparation of said compounds of general formula (I).