1604-08-6

Usage

Uses

Used in Organic Synthesis:
9-XANTHENECARBOXYLIC HYDRAZIDE is used as a reagent in organic synthesis for its ability to contribute to the formation of complex organic molecules, which can be utilized in a variety of chemical processes and products.
Used in Fluorescent Dyes and Pigments:
As a key component in the preparation of fluorescent dyes and pigments, 9-XANTHENECARBOXYLIC HYDRAZIDE is used for its optical properties, enabling the creation of vibrant and luminescent colorants for various applications.
Used in Anti-Tumor Research:
9-XANTHENECARBOXYLIC HYDRAZIDE is used as a potential anti-tumor agent in the field of oncology, where it is studied for its capacity to combat tumor growth and contribute to cancer treatment strategies.
Used in UV-Absorbing Materials:
Leveraging its UV-absorbing properties, 9-XANTHENECARBOXYLIC HYDRAZIDE is used in the development of materials that can protect against harmful ultraviolet radiation, useful in applications such as sunscreens and protective coatings.
Used in Industrial Applications:
9-XANTHENECARBOXYLIC HYDRAZIDE is used in various industrial applications, including the production of specialized dyes and the development of new materials for optical and electronic devices, where its unique chemical properties can enhance performance and functionality.

Upstream product

• 82-07-5 xanthene-9-carboxylic acid 
• 39497-06-8 9H-xanthene-9-carboxylic acid methyl ester 

Downstream Products

• 1264702-29-5 Boc-Tyr(OBn)-NHNH-CO-9H-Xanth 

Relevant academic research and scientific papers

Synthesis of N′-propylhydrazide analogs of hydroxamic inhibitors of histone deacetylases (HDACs) and evaluation of their impact on activities of HDACs and replication of hepatitis C virus (HCV)

N′-Propylhydrazide analogs of hydroxamic inhibitors of histone deacetylases (HDACs), including tubastatin A, vorinostat and belinostat, were synthesized. All prepared compounds inhibited HDAC1/2/3, but not HDAC6, except for one hydrazide analog of HDAC4/5/7 inhibitor that was completely inactive. A novel 4-substituted derivative of N′-propylbenzohydrazide with extremely high anti-HCV activity was discovered.

Microwave irradiation and diisopropylcarbodiimide (DIC)/7-aza-1- hydroxybenzotriazole (HOAt): A potent combination for synthesis of variuos hydrazide from N-protected amino acid and hydrazine

Here we describe a fast and rapid technique for preparation of amino acid hydrazide as well as peptide hydrazide derivatives using diisopropylcarbodiimide (DIC)/1-hydroxybenzotriazoles (HOXt) (X = A or B) under microwave irradiation employing a multimode reactor (Synthos 3000 Aton Paar, GmbH, 1400 W maximum magnetron). A comparison between conventional and microwave irradiation was described. The microwave methodology is rapid, convenient, proceeds under mild conditions. Diisopropylcarbodiimide (DIC)/7-aza-1-hydroxybenzotriazole (HOAt) always gave much better yield (95 - 98%) and purity than diisopropylcarbodiimide (DIC)/1-hydroxybenzotriazole (HOBt).