160427-29-2

Upstream product

• 165878-01-3 3-(5'-O-benzoyl-2',3'-isopropylidene-β-D-ribofuranos-1'-yl)-5-ethoxycarbonyl-4,5-dihydroisoxazole 
• 165878-02-4 ethyl 4-(5'-O-benzoyl-2',3'-isopropylidene-β-D-ribofuranos-1'-yl)-2-hydroxy-4-oxobutenoate 

Relevant academic research and scientific papers

Nitrile oxide [3+2] cycloaddition: Application to the synthesis of 6-substituted 3(2H)-pyridazinones and 6-substituted 4,5-dihydro-4-hydroxy-3(2H)-pyridazinones

An efficient method for the preparation of 6-substituted 3(2H)-pyridazinones and 6-substituted 4,5-dihydro-4-hydroxy-3(2H)-pyridazinones starting from 3,5-disubstituted 4,5-dihydroisoxazoles is described. N-O bond cleavage of the isoxazoline ring promoted