160455-80-1Relevant articles and documents
Synthesis of 3-aryl-5-methyl 4-substituted [1,2,4]triazoles
Lindstroem, Johan,Johansson, Martin
, p. 2217 - 2229 (2007/10/03)
Treatment of N -substituted acetamides with oxalyl chloride generates imidoyl chlorides, which react readily with aryl hydrazides. Following cyclization, triazoles can easily be obtained in moderate to good yields. 5-Methyl triazoles can be further functionalized through α-lithiation and subsequent reaction with an electrophile. Copyright Taylor & Francis Group, LLC.