1604836-41-0Relevant academic research and scientific papers
Ruthenium-catalyzed synthesis of indoles from anilines and epoxides
Pena-Lopez, Miguel,Neumann, Helfried,Beller, Matthias
, p. 1818 - 1824 (2014)
A general synthetic route to indoles from readily available anilines and epoxides by using ruthenium catalysis is described. This straightforward transformation allows a variety of indoles to be obtained in good yields by using [Ru3(CO)12]/1,1-bis(diphenylphosphino)ferrocene as the catalytic system. Water and hydrogen are formed as the only stoichiometric by-products, making this process highly atom efficient.
