160505-19-1

Basic information

• Product Name: (4-(1-phenylbutyl)phenyl)methanol
• Synonyms: (4-(1-phenylbutyl)phenyl)methanol
• CAS NO: 160505-19-1
• Molecular Weight: 240.345
• Mol File: 160505-19-1.mol

Chemical Properties

• CAS DataBase Reference: (4-(1-phenylbutyl)phenyl)methanol(CAS DataBase Reference)
• NIST Chemistry Reference: (4-(1-phenylbutyl)phenyl)methanol(160505-19-1)
• EPA Substance Registry System: (4-(1-phenylbutyl)phenyl)methanol(160505-19-1)

Safety Data

• Hazardous Substances Data: 160505-19-1(Hazardous Substances Data)

Upstream product

• 873-75-6 4-bromobenzenemethanol 
• 13633-25-5 1-Bromo-4-phenylbutane 

Relevant articles and documents

Photochemical Nickel-Catalyzed Reductive Migratory Cross-Coupling of Alkyl Bromides with Aryl Bromides

A novel method to access 1,1-diarylalkanes from readily available, nonactivated alkyl bromides and aryl bromides via visible-light-driven nickel and iridium dual catalysis, wherein diisopropylamine (iPr2NH) is used as the terminal stoichiometric reductant, is reported. Both primary and secondary alkyl bromides can be successfully transformed into the migratory benzylic arylation products with good selectivity. Additionally, this method showcases tolerance toward a wide array of functional groups and the presence of bases.

CONDENSED PYRAZOLE DERIVATIVES, METHOD OF MANUFACTURING THE SAME, AND ANDROGEN INHIBITOR

This invention provides a condensed pyrazole derivative of the Formula (1): STR1 (where A denotes CH or N, R 0 and R 3 denote same or different, a hydrogen atom or a lower alkyl group, R 1 and R 2 denote same or different, a hydrogen atom, a lower alkyl group, a lower alkoxy group, a lower alkylthio group, a nitro group or a halogen atom, m denotes 1 or 2, and n denotes 1, 2 or 3, provided that, when n is 2, two R 2 may be connected to each other to form a lower alkylenedioxy group), or its pharmaceutically acceptable salt. This derivative or its salt is excellent in the effect of inhibiting the expression of action of androgen, thereby being excellent in therapeutical effect of benign prostatic hypertrophy, prostatic carcinoma, etc., and has a long lasting of efficacy and high oral absorption.