160549-18-8

Basic information

• Product Name: methyl 3-methyl-4-oxoretinoate
• Synonyms: methyl 3-methyl-4-oxoretinoate
• CAS NO: 160549-18-8
• Molecular Weight: 342.478
• Mol File: 160549-18-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: methyl 3-methyl-4-oxoretinoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 3-methyl-4-oxoretinoate(160549-18-8)
• EPA Substance Registry System: methyl 3-methyl-4-oxoretinoate(160549-18-8)

Safety Data

• Hazardous Substances Data: 160549-18-8(Hazardous Substances Data)

Upstream product

• 339-16-2 all-trans-methyl retinoate 
• 71748-57-7 4-Oxo-retinoic acid methyl ester 
• 74-88-4 methyl iodide 

Relevant articles and documents

Modification of the intact retinoid structure in the cyclohexenyl region: Alkylation of methyl 4-oxoretinoate

Alkylation of methyl 4-oxoretinoate under kinetic-control conditions gives predominantly 3-alkyl-4-oxoretinoates. 3,3-Disubstituted 4-oxoretinoates are obtained similarly from the 3-monosubstituted derivatives, although introduction of the second substituent is more difficult. Evidence has been obtained for a much slower rate of alkylation α to the ester group.