160568-14-9 Usage
Uses
Used in Pharmaceutical Industry:
Zarzissine is used as a cytotoxic agent for its ability to target and eliminate human and murine tumor cell lines. Its cytotoxic properties make it a potential candidate for the development of new cancer treatments and therapies.
Used in Cancer Research:
In the field of cancer research, zarzissine is used as a compound for studying its effects on various types of cancer cells. This can help researchers better understand the mechanisms of action and potential applications in cancer treatment.
Used in Drug Development:
Zarzissine's cytotoxic activity against tumor cell lines makes it a valuable compound in the development of new drugs for cancer treatment. It can be further studied and modified to improve its efficacy and selectivity towards cancer cells, potentially leading to the creation of more effective and targeted therapies.
Check Digit Verification of cas no
The CAS Registry Mumber 160568-14-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,6,0,5,6 and 8 respectively; the second part has 2 digits, 1 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 160568-14:
(8*1)+(7*6)+(6*0)+(5*5)+(4*6)+(3*8)+(2*1)+(1*4)=129
129 % 10 = 9
So 160568-14-9 is a valid CAS Registry Number.
InChI:InChI=1/C5H5N5/c6-5-9-3-1-7-8-2-4(3)10-5/h1-2H,(H3,6,9,10)
160568-14-9Relevant academic research and scientific papers
Dienophilicity of imidazole in inverse electron demand Diels-Alder reactions: Cycloadditions with 1,2,4,5-tetrazines and the structure of zarzissine
Wan, Zhao-Kui,Woo, Grace H.C.,Snyder, John K.
, p. 5497 - 5507 (2007/10/03)
The inverse electron demand cycloadditions of 2-substituted imidazoles with dimethyl 1,2,4,5-tetrazine-3,6-dicarboxylate produced imidazo[4,5-d]pyridazines in good yields. This chemistry was applied to the synthesis of 2-amino-1H-imidazo[4,5-d]pyridazine (1), the structure reported for zarzissine, a cytotoxic marine alkaloid. Differences in the 1H- and 13C NMR spectra of 1 with those reported for zarzissine necessitated a structural revision, and zarzissine was then considered to be the corresponding 2-amino-1H-imidazo[4,5-b]pyrazine (2), which was subsequently synthesized from the parent heterocycle.
