160590-46-5

Basic information

• Product Name: 4-[(propylamino)methyl]phenol
• Synonyms: 4-[(propylamino)methyl]phenol
• CAS NO: 160590-46-5
• Molecular Formula: C10H15NO
• Molecular Weight: 165.2322
• Mol File: 160590-46-5.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 275.7±15.0 °C(Predicted)
• Appearance: /
• Density: 1.016±0.06 g/cm3(Predicted)
• PKA: 9.41±0.15(Predicted)
• CAS DataBase Reference: 4-[(propylamino)methyl]phenol(CAS DataBase Reference)
• NIST Chemistry Reference: 4-[(propylamino)methyl]phenol(160590-46-5)
• EPA Substance Registry System: 4-[(propylamino)methyl]phenol(160590-46-5)

Safety Data

• Hazardous Substances Data: 160590-46-5(Hazardous Substances Data)

Usage

Synthesis Reference(s)

Journal of Heterocyclic Chemistry, 8, p. 605, 1971 DOI: 10.1002/jhet.5570080413

Upstream product

• 106493-25-8 N-propyl-4-hydroxybenzylideneamine 
• 123-08-0 4-hydroxy-benzaldehyde 
• 107-10-8 propylamine 

Downstream Products

• 1585946-49-1 C₂₁H₂₂N₂OS 

Relevant articles and documents

Methyl-triflate-mediated dearylmethylation of: N -(arylmethyl)carboxamides via the retro-Mannich reaction induced by electrophilic dearomatization/rearomatization in an aqueous medium at room temperature

We have developed a protocol for the dearylmethylation of N-(arylmethyl)carboxamides under metal-free conditions in an aqueous medium at room temperature. This protocol involves methyl triflate-mediated successive C-C and C-N bond cleavages (retro-Mannich reaction) induced by electrophilic dearomatization/rearomatization. The dearomatization/rearomatization strategy can be expected to inspire the development of novel transformations based on the C-C bond cleavage in an environmentally benign manner.

Development of chemosensor for Sr2+ using organic nanoparticles: Application of sensor in product analysis for oral care

A new series of compounds has been developed for the recognition of metal ions and it was found that the position of substituent in the organic compound proved to be the deciding factor for the development of a chemosensor. Reprecipitation method was used

Novel caffeic acid amide antioxidants: Synthesis, radical scavenging activity and performance under storage and frying conditions

Twelve novel dihydro-caffeic acid amides were synthesised in good yields and fully characterised by 1H NMR, 13C NMR, and MS. Their radical scavenging activities were assessed by DPPH assay. Additionally, their abilities to protect polyunsaturated oils under accelerated storage and frying conditions were evaluated. All the new compounds possessed significantly higher radical scavenging activities than α-tocopherol and butylated hydroxytoluene (BHT). The radical scavenging activity of N-decyl-N-(3,5- dimethoxy-4-hydroxybenzyl)-3-(3,4-dihydroxyphenyl) propanamide was 1.7 and 4 times higher than α-tocopherol and BHT, respectively. At the end of the storage period, the respective amounts of hydroperoxides in canola oil triacylglycerols (CTAG) fortified with α-tocopherol and BHT was 6.1 and 1.4 times higher, respectively, than CTAG containing the amide. The frying test showed that CTAG containing N-decyl-N-benzyl-3-(3,4-dihydroxybenzyl) propanamide was 1.3, 1.4, and 1.6 times more stable compared to oil fortified with dihydro-caffeic acid, α-tocopherol and BHT, respectively, as assessed by the amounts of the total polar compounds. Moreover, these compounds were remarkably thermally stable, making them suitable for frying applications.