1606131-61-6Relevant articles and documents
Sequential C3 and C5 direct C-H arylation of imidazo[1,2-a]pyrazines with (Hetero)aryl bromides
Johnson, Brett M.,Huestis, Malcolm P.
, p. 1589 - 1593 (2014/03/21)
An efficient reaction manifold for the preparation of C3/C5- diarylimidazo[1,2-a]pyrazines through sequential C3 and C5 direct arylation is disclosed. The two distinct palladium catalyst systems showcased herein are compatible with a wide variety of aryl and heteroaryl bromides and are also operative in a one-pot, twofold C-H functionalization event. Copyright