1606143-48-9Relevant academic research and scientific papers
Organocatalytic reductive coupling of aldehydes with 1,1-diarylethylenes using an: In situ generated pyridine-boryl radical
Cao, Jia,Wang, Guoqiang,Gao, Liuzhou,Cheng, Xu,Li, Shuhua
, p. 3664 - 3671 (2018)
A pyridine-boryl radical promoted reductive coupling reaction of aldehydes with 1,1-diarylethylenes has been established via a combination of computational and experimental studies. Density functional theory calculations and control experiments suggest that the ketyl radical from the addition of the pyridine-boryl radical to aldehydes is the key intermediate for this C-C bond formation reaction. This metal-free reductive coupling reaction features a broad substrate scope and good functional compatibility.
