16065-26-2

Basic information

• Product Name: N-[3-(trifluoromethyl)benzyl]propan-1-amine
• Synonyms: Benzenemethanamine, N-propyl-3-(trifluoromethyl)-
• CAS NO: 16065-26-2
• Molecular Formula: C₁₁H₁₄F₃N
• Molecular Weight: 217.2308
• Mol File: 16065-26-2.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 220.4°C at 760 mmHg
• Flash Point: 87.1°C
• Density: 1.099g/cm³
• Vapor Pressure: 0.113mmHg at 25°C
• Refractive Index: 1.455
• CAS DataBase Reference: N-[3-(trifluoromethyl)benzyl]propan-1-amine(CAS DataBase Reference)
• NIST Chemistry Reference: N-[3-(trifluoromethyl)benzyl]propan-1-amine(16065-26-2)
• EPA Substance Registry System: N-[3-(trifluoromethyl)benzyl]propan-1-amine(16065-26-2)

Safety Data

• Hazardous Substances Data: 16065-26-2(Hazardous Substances Data)

Upstream product

• 454-89-7 3-Trifluoromethylbenzaldehyde 

Relevant articles and documents

Benzylamines: Synthesis and evaluation of antimycobacterial properties

The synthesis of benzylamines with various N-alkyl chains and substituents in the aromatic system as well as their evaluation on Mycobacterium tuberculosis H 37 Ra are described. The most active compounds in this test, N-methyl-3-chlorobenzylamine (MIC 10.2 μg/mL), N-methyl-3,5-dichlorobenzylamine (93, MIC 10.2 μg/mL), and N-butyl-3,5-difluorobenzylamine (MIC 6.4 μg/mL), also exhibited a marked inhibitory effect on Mycobacterium marinum and Mycobacterium lufu used for the determination of antileprotic properties. The combination of 93 with aminosalicylic acid, streptomycin, or dapsone exert marked supra-additive effects on M. tuberculosis H 37 Ra.