16067-61-1

Upstream product

• 85-44-9 phthalic anhydride 
• 613-94-5 benzoic acid hydrazide 

Downstream Products

• 16067-65-5 N-(1,3-dioxo-1,3-dihydroisoindol-2-yl)-benzamide 
• 1483-24-5 1-methyl-1-benzoylhydrazine 
• 38663-32-0 1-benzyl-1-benzoylhydrazine 
• 287729-09-3 N-methyl-N-benzoylaminophthalimide 
• 287729-10-6 N-benzyl-N-benzoylaminophthalimide 

Relevant academic research and scientific papers

New Synthesis of 1,1-Substituted Hydrazines by Alkylation of N-Acyl- or N-alkyloxycarbonylaminophthalimide Using the Mitsunobu Protocol

N-acyl- and N-alkoxycarbonylaminophthalimides are prepared using a convenient reaction and are efficiently used as acid partners in Mitsunobu reaction. This reaction allows them to be alkylated by primary, secondary or benzyl groups. Comparison of the reactivities and pKa values of these N-substituted aminophthalimides suggest that the success of the Mitsunobu reaction in this case seems to be governed more by steric than by electronic effects. A final dephthaloylation step results in an efficient method for the preparation of 1,1-substituted hydrazines.

Synthesis and Spectra of Some Phthalimido Derivatives

The reactions of some aroylhydrazines and amino derivatives of heterocyclic compounds with phthalic anhydride were investigated.Dehydration of the prepared carboxybenzoyl derivatives afforded the corresponding phthalimido products.The structures were confirmed by IR, proton NMR, and mass spectra.

Oxadiazole benzoic acid derivatives as herbicides

New 2-(1,3,4-oxadiazole-2-yl) benzoic acids and salts and esters thereof, as well as certain 2-(2-oxazolyl) benzoic acids, salts and esters, having the formula: SPC1 Where X is nitrogen or C-R" (R" being hydrogen or methyl), R is phenyl or various substituents, and R' and the Y's are hydrogen or various substituents, are effective preemergence or postemergence herbicides, on various crops. The chemicals act selectively and are useful against purple nutsedge and in cranberry. Oxadiazoles of the invention may be made by reacting a benzhydrazide with phthalic anhydride to form a hydrazide which is cyclized by removal of the elements of water, using as a catalyst fuming sulfuric acid or dimethylformamide-sulfur trioxide complex.