160682-43-9Relevant academic research and scientific papers
The regiochemistry of carbenoid insertion into zirconacycles
Gordon, George J.,Luker, Tim,Tuckett, Mark W.,Whitby, Richard J.
, p. 2113 - 2129 (2007/10/03)
The regioselectivity of insertion of lithium chloroallylides (allyl carbenoids) into a wide variety of unsymmetrical zirconacycles has been determined. In all but one case a single regioisomer was obtained. A combination of steric and electronic effects is needed to explain the results and imply that the carbenoid is acting predominantly as an electrophilic species. The first carbenoid insertion into a zirconacyclopentadiene is noted. (C) 2000 Elsevier Science Ltd.
Novel synthesis of nitrogen heterocycles using zirconium-promoted reductive cyclization
Mori,Uesaka,Saitoh,Shibasaki
, p. 5643 - 5649 (2007/10/02)
Perhydroindole derivatives were prepared from enynes using zirconium-promoted reductive cyclization. The zirconacycles derived from enynes 1 were treated with iodine, isonitriles, oxygen, and carbon monoxide to give various heterocycles. The carbon-zirconium bonds of the zirconacycle could be selectively cleaved by different reagents.
